郭敏,中国药科大学生命科学与技术学院副教授。2015年毕业于中国科学院武汉病毒研究所,长期致力于HBV,HCV,呼吸道合胞病毒和流感病毒研究,方向有病毒与宿主相互作用,抗病毒药物筛选及机制研究。
抗病毒药物筛选及病毒与宿主相互作用。 |
1. 可吸收性外科缝合线抑菌性能动物试验方案8230040036
2. FGF21-164融合蛋白成药性的研究8210040034
3. CLK2小分子抑制剂的研发合作8220010096
4. pBSK-HBV1.3-nanoKAZ复制子质粒的鉴定及病毒包装,鉴定和抗病毒筛选的应用8230040044(
5. 改造痘苗病毒构建基因治疗的递送系统8230040046(
6. 中央高校基本科研业务费专项资金重点项目,2632021ZD20,调控肝脏糖异生新靶点PNPLA7的研究。资助经费:15万元,资助时间:2021.01-2022.12,已结题。
7. 国家自然科学基金青年科学基金项目, 81700756,PNPLA7调控肝脏糖异生的机制及在HCV相关糖异生紊乱中的作用。资助经费:20万元,资助时间:2018.01-2020.12,已结题。
1. Wang MR, Tian BP, Shen J, Xu SL, Liu C, Guan L, Guo M*, Dou J*. 2023. Bavachin induces apoptosis in colorectal cancer cells through Gadd45a via the MAPK signaling pathway. Chinese Journal of Natural Medicines 21:36-46.(共通排二,IF:4.600)
2. Deng WY, Chen F, Zhao Y, Zhou M*, Guo M*. 2023. Anti-hepatitis B virus activities of natural products and their antiviral mechanisms. Chinese Journal of Natural Medicines 21(11): 803-811(共通排一,IF:4.600)
3. Chen S, Qin B, Zhou CL, Yu HF, Deng WY, Yao YX*, Guo M*. 2023. Strongylocentrotus nudus egg polysaccharide (SEP) suppresses HBV replication via activation of TLR4-induced immune pathway. International Journal of Biological Macromolecules 245. (共通排一,IF: 8.025 )
4. Zhang X, Su HL, Yu HF, Ding JL, Deng WY, Qin B, Zhou CL*, Dou J*, Guo M*. 2022. A Polysaccharide From Walker With Anti- HBV Activities and. Frontiers in Pharmacology 13. (共通排一,IF: 5.988 )
5. Li MW, Wang YX, Jin J, Dou J, Guo QL, Ke X, Zhou CL*, Guo M*. 2021. Inhibitory Activity of Honeysuckle Extracts against
Influenza A Virus. Virologica Sinica 36:490-500. (共通排一,IF: 6.947 )
6. Tian XL#, Guo M#, Zhang XY, Guo LF, Lan N, Cheng YJ, Han YN, Wang MX, Peng ZL, Zhou CL, Fan HY. 2022. Eggs Polysaccharide Enhances Macrophage Phagocytosis Against Infection by TLR4/STAT3 Axis. Frontiers in Pharmacology 13.
(共一排二,IF: 5.988 )
7. Wang XY#, Guo M#, Wang Q#, Wang QJ, Zuo SS, Zhang X, Tong H, Chen JZ, Wang HM, Chen XW, Guo JY, Su X, Liang H, Zhou HW, Li JZ. 2020. The Patatin-Like Phospholipase Domain Containing Protein 7 Facilitates VLDL Secretion by Modulating ApoE Stability. Hepatology 72:1569-1585.(共一排二,IF:14.679)