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刘晓敏
职称:教授
邮箱:liuxm642@cpu.edu.cn
学院:生命科学与技术学院
实验室:江宁校区教学楼B205室
招生学科:生物学
办公室:江宁校区教学楼B205室
个人简历

1)国家自然科学基金面上项目(2021-2024,主持)

2)“江苏特聘教授”人才计划(2021-2024,主持)

3)“十四五”国家重点研发计划(2023-2026,参与)

4)江苏省自然科学基金面上项目(2021-2024,主持)

5)南京市留学人员科技创新优秀项目(2022-2023,主持)

6)中国药科大学高层次人才科研启动基金(2020,主持)

研究方向

RNA分子调控与细胞命运

主持在研项目情况

1)国家自然科学基金面上项目(2021-2024,主持)

2)“江苏特聘教授”人才计划(2021-2024,主持)

3)“十四五”国家重点研发计划(2023-2026,参与)

4)江苏省自然科学基金面上项目(2021-2024,主持)

5)南京市留学人员科技创新优秀项目(2022-2023,主持)

6)中国药科大学高层次人才科研启动基金(2020,主持)

近年代表性科研成果

1Wang Y#, Wang S#, Meng Z#, Liu XM*, Mao Y*. Determinant of m6A regional preference by transcriptional dynamics. (2024) Nucleic Acids Research 52(7):3510-3521

2Wang F#, Zhang J#, Lin X#, Yang L, Zhou Q, Mi X, Li Q, Wang S, Li D, Liu XM*, Zhou J*. METTL16 promotes translation and lung tumorigenesis by sequestering cytoplasmic eIF4E2. (2023) Cell Reports 42(3):112150

3Qin M#, Huang L#, Li M#, Shao T, Zhang J, Jiang X, Shao C, Zhao C, Pan Y, Zhou Q*, Wang Y, Liu XM*, Qiu J*. Immunotoxicity Evaluation of Trihalophenolic Disinfection By-Products in Mouse and Human Mononuclear Macrophage Systems: The Role of RNA Epitranscriptomic Modification in Mammalian Immunity. (2023) Environmental Health Perspectives 131(12):127023

4Liu XM#*, Mao Y#, Wang S, Zhou J, Qian SB*. METTL3 modulates chromatin and transcription dynamics during cell fate transition. (2022) Cellular and Molecular Life Sciences 79(11): 559

5Liu XM*, Zhou J*. Multifaceted regulation of translation by the epitranscriptomic modification N6-methyladenosine. (2021) Critical Reviews in Biochemistry and Molecular Biology 56(2): 137-148

6Liu XM*, Wang S, Gan X, Qian SB, Zhou J*. Fluorescein-based monitoring of RNA N6-methyladenosine at single-nucleotide resolution. (2021) Journal of Molecular Cell Biology13(4): 325-328

7Wang S, Zhang J, Wu X, Lin X, Liu XM*, Zhou J*. Differential roles of YTHDF1 and YTHDF3 in embryonic stem cell-derived cardiomyocyte differentiation. (2021) RNA Biology 18(9): 1354-1363

8Liu XM, Zhou J, Mao Y, Ji QQ, Qian SB*. Programmable RNA N6-methyladenosine editing using CRISPR/Cas9 conjugates. (2019) Nature Chemical Biology 15(9): 865-871

9Liu XM and Qian SB*. Assembly en route. (2019) Nature Structural & Molecular Biology 26: 89-91

10Coots RA#, Liu XM#, Mao Y, Dong L, Zhou J, Wan J, Zhang X, Qian SB*. m6A facilitates eIF4F-independent mRNA translation. (2017) Molecular Cell 68(3): 504-514