潘怡,女,博士,生命科学与技术学院副教授,微生物与生化药学专业硕士生导师。
教育经历:
2007.9-2011.6,南京大学生命科学学院,生物学专业,学士学位
2011.9-2016.6,南京大学生命科学学院,生物化学与分子生物学专业,博士学位
肿瘤 |
1.主持国家自然科学基金青年项目一项:miR-210在乳腺癌干细胞自我更新和侵袭转移中的作用及机制研究(项目编号:81702941;经费:20万元)
2. 主持国家自然科学基金面上项目一项:乳腺癌干细胞外泌体lncRNA-RPPH1促进转移发生和预转移微环境形成的机制研究(项目编号:82073227;经费:55万元)
1) Tingting Tang#, Zhaocong Yang, Qinhua Zhu, You Wu, Kun Sun, Murad Alahdal, Yanfeng Zhang, Yun Xing, Yumeng Shen, Tiansong Xia, Tao Xi, Yi Pan*, Liang Jin*. Up-regulation of miR-210 induced by a hypoxic microenvironment promotes breast cancer stem cells metastasis, proliferation, and self-renewal by targeting E-cadherin. FASEB J 2018; 12:6.
2) Tingting Tang#, Changying Guo, Tiansong Xia, Rui Zhang, Ke Zen, Yi Pan*, Liang Jin*. LncCCAT1 Promotes Breast Cancer Stem Cell Function through Activating WNT/beta-catenin Signaling. Theranostics 2019; 9: 7384-7402.
3) Wanyue Shi#, Tingting Tang#, Xinping Li#, Siwei Deng, Ruiyi Li, Yingshan Wang, Yifei Wang, Tiansong Xia, Yanfeng Zhang, Ke Zen, Liang Jin*,Yi Pan*. Methylation-mediated silencing of miR-133a-3p promotes breast cancer cell migration and stemness via miR-133a-3p/MAML1/DNMT3A positive feedback loop. J Exp Clin Cancer Res 2019; 38: 429.
4) You Wu#, Wanyue Shi#, Tingting Tang#, Yidong Wang, Xin Yin, Yanlin Chen, Yanfeng Zhang, Yun Xing, Yumeng Shen, Tiansong Xia, Changying Guo, Yi Pan*, Liang Jin*. miR-29a contributes to breast cancer cells epithelial-mesenchymal transition, migration, and invasion via down-regulating histone H4K20 trimethylation through directly targeting SUV420H2. Cell Death Dis 2019; 10: 176.
5) Tingting Tang#, Qinhua Zhu#, Xinping Li, Gaole Zhu, Siwei Deng, Yingshan Wang, Lingyu Ni, Xinyuan Chen, Yanfeng Zhang, Tiansong Xia, Ke Zen, Yi Pan*, Liang Jin*. Protease Nexin I is a feedback regulator of EGF/PKC/MAPK/EGR1 signaling in breast cancer cells metastasis and stemness. Cell Death Dis 2019; 10: 649.
6) Xinping Li#, Siwei Deng#, Xinyao Pang, Yixiao Song, Shiyu Luo, Liang Jin, Yi Pan*. LncRNA NEAT1 Silenced miR-133b Promotes Migration and Invasion of Breast Cancer Cells. Int J Mol Sci 2019; 20.
7) Manman Li#, Pandi Wu#, Zhaocong Yang#, Siwei Deng, Lingyu Ni, Yanfeng Zhang*, Liang Jin*, Yi Pan*. miR-193a-5p Promotes Pancreatic Cancer Cell Metastasis Through SRSF6-mediated Alternative Splicing of OGDHL and ECM1. Am J Cancer Res 2020; 10: 38-59.
8) Xin Yin #, Jingyan Yang #, Jintian Chen #, Ruiqi Ni, Yanhao Zhou, Hao Song, Liang Jin, Tingting Tang*, Yi Pan*. LncRNA CTD-3252C9.4 modulates pancreatic cancer cell survival and apoptosis through regulating IFI6 transcription. Cancer Cell Int. 2021;16;21(1):433.
9) Xinping Li #, Jingyan Yang #, Ruiqi Ni, Jintian Chen, Yanhao Zhou, Hao Song, Liang Jin*, Yi Pan*. Hypoxia-induced lncRNA RBM5-AS1 promotes tumorigenesis via activating Wnt/β-catenin signaling in breast cancer. Cell Death Dis 2022;2;13(2):95.