(1)Yubin Zhang, Thomas W. Gettys,etc. Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1α.The Journal of Biological Chemistry, 2009, 284(47):32813-32826
(2)Yubin Zhang, Thomas W. Gettys,etc. Targeted deletion of melanocortin receptor subtypes 3 and 4, but not CART, alters nutrient partitioning and compromises behavioral and metabolic responses to leptin. The FASEB Journal , 2005,19:1482-1491
(3)Pengcheng Zhang,Yubin Zhang,etc. Demethyleneberberine, a Natural Mitochondria-Targeted A ntioxidant, Inhibits Mitochondrial Dysfunction, Oxidative Stress, and Steatosis in Alcoholic Liver Disease Mouse Models, J Pharmacol Exp Ther(JPET), 2015, 352:139-147
(4)张玉彬,张元强,闻婧等.盐酸去亚甲基四氢小檗碱在制备预防或治疗酒精性肝病和非酒精性脂肪肝病药物中的应用(授权专利CN109432096B)
(5)张玉彬,葛闯,韩彦红.盐酸去亚甲基小檗碱在制备治疗肺纤维化药物中的应用(授权专利CN115192573B)
(6) 张玉彬 ,陈盈盈, 闫岩 等,DMB在制备预防和/或治疗溃疡性结肠炎药物中的应用.(授权利(ZL201410260577.6 )
(7)张玉彬,闻婧,刘东晴 等.盐酸去亚甲基四氢小檗碱在制备预防或治疗神经退行性疾病药物中的应用(授权专利CN112043700B)
(8)Crystal Forms of Demethyleneberberine Hydrochloride and Preparation Method Therefor(PCT Pub No:WO2019/153644,PCT-US 11242340
(9)张玉彬 编著 《生物催化的手性合成》,北京:化学工业出版社,2001
(10)张玉彬 主编 《生物化学与分子生物学》,北京:人民卫生出版社,2019
代谢性疾病的基础与药物治疗研究 |
(1)去亚甲基小檗碱调控NT-PGC-1α和靶向线粒体抗氧化治疗非酒精性脂肪肝作用与机制(国自然项目 81573484)
(2)NT-PGC1α在β3-AR激动剂治疗肥胖症中的作用与机制研究(国自然项目81072679)
(1)Yubin Zhang, Thomas W. Gettys,etc. Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1α.The Journal of Biological Chemistry, 2009, 284(47):32813-32826
(2)Yubin Zhang, Thomas W. Gettys,etc. Targeted deletion of melanocortin receptor subtypes 3 and 4, but not CART, alters nutrient partitioning and compromises behavioral and metabolic responses to leptin. The FASEB Journal , 2005,19:1482-1491
(3)Pengcheng Zhang,Yubin Zhang,etc. Demethyleneberberine, a Natural Mitochondria-Targeted A ntioxidant, Inhibits Mitochondrial Dysfunction, Oxidative Stress, and Steatosis in Alcoholic Liver Disease Mouse Models, J Pharmacol Exp Ther(JPET), 2015, 352:139-147
(4)张玉彬,张元强,闻婧等.盐酸去亚甲基四氢小檗碱在制备预防或治疗酒精性肝病和非酒精性脂肪肝病药物中的应用(授权专利CN109432096B)
(5)张玉彬,葛闯,韩彦红.盐酸去亚甲基小檗碱在制备治疗肺纤维化药物中的应用(授权专利CN115192573B)
(6) 张玉彬 ,陈盈盈, 闫岩 等,DMB在制备预防和/或治疗溃疡性结肠炎药物中的应用.(授权利(ZL201410260577.6 )
(7)张玉彬,闻婧,刘东晴 等.盐酸去亚甲基四氢小檗碱在制备预防或治疗神经退行性疾病药物中的应用(授权专利CN112043700B)
(8)Crystal Forms of Demethyleneberberine Hydrochloride and Preparation Method Therefor(PCT Pub No:WO2019/153644,PCT-US 11242340
(9)张玉彬 编著 《生物催化的手性合成》,北京:化学工业出版社,2001
(10)张玉彬 主编 《生物化学与分子生物学》,北京:人民卫生出版社,2019