1、基于不同载体或佐剂的病毒治疗性疫苗的研究与应用

2、纳米颗粒-生物大分子相互作用及纳米材料的生物毒性研究

3、基于靶向递送系统在体改造免疫细胞用于肿瘤治疗的研究

1. 江苏省自然科学基金青年项目，负载anti-EDB CAR mRNA的中性脂质体在体改造巨噬细胞用于实体瘤治疗的研究, BK20221030，2022-2025，主持

1. Liu, Shang; Wang, Zhenzhen; Jiang, Xinbang; Gan, Jingjing; Tian, Xuejiao; Xing, Zhen; Yan, Yiqing; Chen, Jiahui; Zhang, Junfeng; Wang, Chunming; Dong, Lei; Denatured corona proteins mediate the intracellular bioactivities of nanoparticles via the unfolded protein response, Biomaterials, 2020, 265: 120452

2. Liu, Shang; Jiang, Xinbang; Tian, Xuejiao; Wang, Zhenzhen; Xing, Zhen; Chen, Jiahui; Zhang, Junfeng; Wang, Chunming; Dong, Lei; A method to measure the denatured proteins in the corona of nanoparticles based on the specific adsorption of Hsp90ab1, Nanoscale, 2020, 12(29): 15857-15868