1. MinZhou, HuiShe#, ChuanHuang#. Lysosomes join the circular RNA decay machinery. Trends in Cell Biology (2026).
2. Shiyuan Chen*, Canchen*, Wang, Junyi Hu, Ting Luo, Qian Li#, Hui Shen#. Noncoding RNAs are indispensable architects and regulators of biomolecular condensates. Non-coding RNA Research(2026).
3. Minxiang Zhong*, Shiyuan Chen*, Wengqi Lu, Ting Luo, Ruiya Shi, Jinzhou Li, Hui Shen#. Liquid-liquid phase separation of DDX3X: mechanisms, pathological implications, and therapeutic potential. International Journal of Biological Macromolecules (2025).
4. Michael C Owens*, Hui Shen*, Amber Yanas, Maria Saraí Mendoza-Figueroa, Ellen Lavorando, Xiaoyu Wei, Him Shweta, Hsin-Yao Tang, Yale E Goldman#, Kathy Fange Liu#. Specific catalytically impaired DDX3X mutants form sexually dimorphic hollow condensates. Nature Communications (2024).
5. Yulia Gonskikh*, Julian Stoute*, Hui Shen*, Krista Budinich, Bianca Pingul, Kollin Schultz, Heidi Elashal, Ronen Marmorstein, Junwei Shi, Kathy Fange Liu#. Noncatalytic regualtion of 18S rRNA methyltransferase DIMT1 in acute myeloid leukemia. Genes and Development (2023).
6. Hui Shen*, Amber Yanas*, Michael C Owens, Celia Zhang, Clark Fritsch, Charlotte M Fare, Katie E Copley, James Shorter, Yale E Goldman, Kathy Fange Liu#. Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation. Molecular cell (2022).
7. Hui Shen, Yulia Gonskikh, Julian Stoute, Kathy Fange Liu#. Human DIMT1 generates N26, 6A-dimethylation–containing small RNAs. Journal of Biological Chemistry (2021).
8. Hui Shen, Robert Jordan Ontiveros, Michael C Owens, Monica Yun Liu, Uday Ghanty, Rahul M Kohli, Kathy Fange Liu#. Journal of Biological Chemistry (2021).
9. Hui Shen, Julian Stoute, Kathy Fange Liu#. Structural and catalytic roles of the human 18S rRNA methyltransferases DIMT1 in ribosome assembly and translation. Journal of Biological Chemistry (2020).
10. R Jordan Ontiveros*, Hui Shen*, Julian Stoute, Amber Yanas, Yixiao Cui, Yuyu Zhang, Kathy Fange Liu#. Coordination of mRNA and tRNA methylations by TRMT10A. Proceedings of the National Academy of Sciences (2020).
11. Shuhuai Yu*, Hui Shen*, Yuanyuan Cheng, Yingying Zhu, Xu Li#, Wanmeng Mu#. Structural and functional basis of difructose anhydride III hydrolase, which sequentially converts inulin using the same catalytic residue. ACS Catalysis (2018).
12. Hui Shen*, Yuwei Zhu*, Chongyuan Wang, Hui Yan, Maikun Teng, Xu Li#. Structural and histone binding ability characterization of the ARB2 domain of a histone deacetylase Hda1 from Saccharomyces cerevisiae. Scientific reports (2016).
13. Hui Shen*, Hong Wang*, Qiao Liu, Huihui Liu, Maikun Teng, Xu Li#. Structural insights into RNA recognition properties of glyceraldehyde‐3‐phosphate dehydrogenase 3 from Saccharomyces cerevisiae. IUBMB life (2014).
14. Hui Shen, Huihui Liu, Hong Wang, Maikun Teng, Xu Li#. Preliminary crystallographic analysis of RraB from Escherichia coli. Acta Crystallographica Section F: Structural Biology and Crystallization Communications (2013).
RNA结合蛋白液-液相分离性质在基因表达调控中的功能及机制
1. 2024年江苏省青年基金项目(BK20241585)。
2. 2024年南京市留学人员科技创新项目择优资助。
3. 国自然青年基金(32500485)。
1. MinZhou, HuiShe#, ChuanHuang#. Lysosomes join the circular RNA decay machinery. Trends in Cell Biology (2026).
2. Shiyuan Chen*, Canchen*, Wang, Junyi Hu, Ting Luo, Qian Li#, Hui Shen#. Noncoding RNAs are indispensable architects and regulators of biomolecular condensates. Non-coding RNA Research(2026).
3. Minxiang Zhong*, Shiyuan Chen*, Wengqi Lu, Ting Luo, Ruiya Shi, Jinzhou Li, Hui Shen#. Liquid-liquid phase separation of DDX3X: mechanisms, pathological implications, and therapeutic potential. International Journal of Biological Macromolecules (2025).
4. Michael C Owens*, Hui Shen*, Amber Yanas, Maria Saraí Mendoza-Figueroa, Ellen Lavorando, Xiaoyu Wei, Him Shweta, Hsin-Yao Tang, Yale E Goldman#, Kathy Fange Liu#. Specific catalytically impaired DDX3X mutants form sexually dimorphic hollow condensates. Nature Communications (2024).
5. Yulia Gonskikh*, Julian Stoute*, Hui Shen*, Krista Budinich, Bianca Pingul, Kollin Schultz, Heidi Elashal, Ronen Marmorstein, Junwei Shi, Kathy Fange Liu#. Noncatalytic regualtion of 18S rRNA methyltransferase DIMT1 in acute myeloid leukemia. Genes and Development (2023).
6. Hui Shen*, Amber Yanas*, Michael C Owens, Celia Zhang, Clark Fritsch, Charlotte M Fare, Katie E Copley, James Shorter, Yale E Goldman, Kathy Fange Liu#. Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation. Molecular cell (2022).
7. Hui Shen, Yulia Gonskikh, Julian Stoute, Kathy Fange Liu#. Human DIMT1 generates N26, 6A-dimethylation–containing small RNAs. Journal of Biological Chemistry (2021).
8. Hui Shen, Robert Jordan Ontiveros, Michael C Owens, Monica Yun Liu, Uday Ghanty, Rahul M Kohli, Kathy Fange Liu#. Journal of Biological Chemistry (2021).
9. Hui Shen, Julian Stoute, Kathy Fange Liu#. Structural and catalytic roles of the human 18S rRNA methyltransferases DIMT1 in ribosome assembly and translation. Journal of Biological Chemistry (2020).
10. R Jordan Ontiveros*, Hui Shen*, Julian Stoute, Amber Yanas, Yixiao Cui, Yuyu Zhang, Kathy Fange Liu#. Coordination of mRNA and tRNA methylations by TRMT10A. Proceedings of the National Academy of Sciences (2020).
11. Shuhuai Yu*, Hui Shen*, Yuanyuan Cheng, Yingying Zhu, Xu Li#, Wanmeng Mu#. Structural and functional basis of difructose anhydride III hydrolase, which sequentially converts inulin using the same catalytic residue. ACS Catalysis (2018).
12. Hui Shen*, Yuwei Zhu*, Chongyuan Wang, Hui Yan, Maikun Teng, Xu Li#. Structural and histone binding ability characterization of the ARB2 domain of a histone deacetylase Hda1 from Saccharomyces cerevisiae. Scientific reports (2016).
13. Hui Shen*, Hong Wang*, Qiao Liu, Huihui Liu, Maikun Teng, Xu Li#. Structural insights into RNA recognition properties of glyceraldehyde‐3‐phosphate dehydrogenase 3 from Saccharomyces cerevisiae. IUBMB life (2014).
14. Hui Shen, Huihui Liu, Hong Wang, Maikun Teng, Xu Li#. Preliminary crystallographic analysis of RraB from Escherichia coli. Acta Crystallographica Section F: Structural Biology and Crystallization Communications (2013).
