博士,研究员,博士生导师。2001年毕业于武汉大学生命科学学院生命科学专业以及武汉大学能源与动力学院热能与动力工程,获得理学与工学双学士学位。2014年毕业于南京大学生命科学学院,获得理学博士学位。2015-2016于南京大学生命科学学院从事博士后研究。2016-2021于美国Morehouse School of Medicine先后从事博士后研究以及Research Associate的工作。承担/参与过多项各级科学基金项目(国家自然科学基金、973等)。在国内外有影响的刊物上(JACI,Nat Micro,Nat Commun,Stem R&Th, Plos Path.等)发表过研究论文二十多篇。
微生物与免疫、疾病与免疫
1.Zhang, M., Johnson-Stephenson, T.K., Wang, W., Wang, Y., Li, J., Li, L., Zen, K., Chen, X., and Zhu, D. (2022). Mesenchymal stem cell-derived exosome-educated macrophages alleviate systemic lupus erythematosus by promoting efferocytosis and recruitment of IL-17(+) regulatory T cell. Stem Cell Res Ther 13, 484. 10.1186/s13287-022-03174-7.
2.Zhu, D., Johnson, T.K., Wang, Y., Thomas, M., Huynh, K., Yang, Q., Bond, V.C., Chen, Y.E., and Liu, D. (2020). Macrophage M2 polarization induced by exosomes from adipose-derived stem cells contributes to the exosomal proangiogenic effect on mouse ischemic hindlimb. Stem Cell Res Ther 11, 162. 10.1186/s13287-020-01669-9.
3.Zhu, D., Pan, C., Sheng, J., Liang, H., Bian, Z., Liu, Y., Trang, P., Wu, J., Liu, F., Zhang, C.Y., and Zen, K. (2018). Human cytomegalovirus reprogrammes haematopoietic progenitor cells into immunosuppressive monocytes to achieve latency. Nat Microbiol 3, 503-513. 10.1038/s41564-018-0131-9.
4.Zhu, D., Wang, Y., Thomas, M., McLaughlin, K., Oguljahan, B., Henderson, J., Yang, Q., Chen, Y.E., and Liu, D. (2022). Exosomes from adipose-derived stem cells alleviate myocardial infarction via microRNA-31/FIH1/HIF-1alpha pathway. J Mol Cell Cardiol 162, 10-19. 10.1016/j.yjmcc.2021.08.010.
5.Zhu, D., Pan, C., Li, L., Bian, Z., Lv, Z., Shi, L., Zhang, J., Li, D., Gu, H., Zhang, C.Y., et al. (2013). MicroRNA-17/20a/106a modulate macrophage inflammatory responses through targeting signal-regulatory protein alpha. J Allergy Clin Immunol 132, 426-436 e428. 10.1016/j.jaci.2013.02.005.