Li Y#, Wang Y#, Tan YQ#, Yue Q#, Guo Y#, Yan R#, Meng L#, Zhai H, Tong L, Yuan Z, Li W, Wang C, Han S, Ren S, Yan Y, Wang W, Gao L, Tan C, Hu T, Zhang H, Liu L, Yang P, Jiang W, Ye Y, Tan H, Wang Y, Lu C, Li X, Xie J, Yuan G, Cui Y, Shen B, Wang C, Guan Y, Li W, Shi Q, Lin G, Ni T, Sun Z, Ye L, Vourekas A, Guo X*, Lin M*, Zheng K*. The landscape of RNA-binding proteins in mammalian spermatogenesis. Science. 2024 Oct 25;386(6720):eadj8172.
Qian B#, Li Y#, Yan R#, Han S#, Bu Z#, Gong J, Zheng B, Yuan Z, Ren S, He Q, Zhang J, Xu C, Wang R, Sun Z, Lin M*, Zhou J*, Ye L*. RNA binding protein RBM46 regulates mitotic-to-meiotic transition in spermatogenesis. Science Advances. 2022 Aug 26;8(34):eabq2945.
Li Y#, Zhai H#, Tong L#, Wang C, Xie Z, Zheng K*. LncRNA Functional Screening in Organismal Development. Noncoding RNA. 2023 Jun 28;9(4):36.
Chen Z#, ling L#, Shi X#, Li W#, Zhai H#, Kang Z, Zheng B, Zhu J, Ye S, Wang H, Tong L, Ni J, Huang C*, Li Y*, Zheng K*. Microinjection of antisense oligonucleotides into living mouse testis enables lncRNA function study. Cell & Bioscience. 2021 Dec 17;11(1):213.
Li Y#, Sha Y#, Wang X#, Ding L#, Liu W, Ji Z, Mei L, Huang X, Lin S, kong S, Lu J, Qin W, Zhang X, Zhuang J*, Tang Y*, Lu Z*. DNAH2 is a novel candidate gene associated with multiplemorphological abnormalities of the sperm flagella. Clinical Genetics. 2019 May;95(5):590-600.
Liu W#, Sha Y#, Li Y#, Mei L, Lin S, Huang X, Lu J, Ding L, Kong S, Lu Z*. Loss-of-function mutations in SPEF2 cause multiple morphological abnormalities of the sperm flagella (MMAF). Journal Of Medical Genetics. 2019 Oct;56(10):678-684.
Li Y#, Liu W#, Yi J, Kong S, Ding J, Zhao Y, Tian Y, Feng G, Li C, Liu W*, Wang H, Lu Z*. The role of tyrosine phosphatase Shp2 in spermatogonial differentiation and spermatocyte meiosis. Asian Journal of Andrology. 2020 Jan-Feb;22(1):79-87.
探究器官发育和相关疾病中RNA结合蛋白的功能和作用机制
利用系统生物学手段发掘、鉴定器官发育中的全新功能性LncRNA,并深入研究其作用机制
开发研究蛋白质-RNA互作的新型高通量技术
国家自然科学基金青年项目(主持) RNA解旋酶D1PAS1在雄性减数分裂中的作用机制研究 10/26/2020 -12/31/2023
中国国家博士后基金(主持)2020M671540 非典型RNA结合蛋白TEX30在精子变形中的作用机制研究 10/19/2021 -12/31/2022
Li Y#, Wang Y#, Tan YQ#, Yue Q#, Guo Y#, Yan R#, Meng L#, Zhai H, Tong L, Yuan Z, Li W, Wang C, Han S, Ren S, Yan Y, Wang W, Gao L, Tan C, Hu T, Zhang H, Liu L, Yang P, Jiang W, Ye Y, Tan H, Wang Y, Lu C, Li X, Xie J, Yuan G, Cui Y, Shen B, Wang C, Guan Y, Li W, Shi Q, Lin G, Ni T, Sun Z, Ye L, Vourekas A, Guo X*, Lin M*, Zheng K*. The landscape of RNA-binding proteins in mammalian spermatogenesis. Science. 2024 Oct 25;386(6720):eadj8172.
Qian B#, Li Y#, Yan R#, Han S#, Bu Z#, Gong J, Zheng B, Yuan Z, Ren S, He Q, Zhang J, Xu C, Wang R, Sun Z, Lin M*, Zhou J*, Ye L*. RNA binding protein RBM46 regulates mitotic-to-meiotic transition in spermatogenesis. Science Advances. 2022 Aug 26;8(34):eabq2945.
Li Y#, Zhai H#, Tong L#, Wang C, Xie Z, Zheng K*. LncRNA Functional Screening in Organismal Development. Noncoding RNA. 2023 Jun 28;9(4):36.
Chen Z#, ling L#, Shi X#, Li W#, Zhai H#, Kang Z, Zheng B, Zhu J, Ye S, Wang H, Tong L, Ni J, Huang C*, Li Y*, Zheng K*. Microinjection of antisense oligonucleotides into living mouse testis enables lncRNA function study. Cell & Bioscience. 2021 Dec 17;11(1):213.
Li Y#, Sha Y#, Wang X#, Ding L#, Liu W, Ji Z, Mei L, Huang X, Lin S, kong S, Lu J, Qin W, Zhang X, Zhuang J*, Tang Y*, Lu Z*. DNAH2 is a novel candidate gene associated with multiplemorphological abnormalities of the sperm flagella. Clinical Genetics. 2019 May;95(5):590-600.
Liu W#, Sha Y#, Li Y#, Mei L, Lin S, Huang X, Lu J, Ding L, Kong S, Lu Z*. Loss-of-function mutations in SPEF2 cause multiple morphological abnormalities of the sperm flagella (MMAF). Journal Of Medical Genetics. 2019 Oct;56(10):678-684.
Li Y#, Liu W#, Yi J, Kong S, Ding J, Zhao Y, Tian Y, Feng G, Li C, Liu W*, Wang H, Lu Z*. The role of tyrosine phosphatase Shp2 in spermatogonial differentiation and spermatocyte meiosis. Asian Journal of Andrology. 2020 Jan-Feb;22(1):79-87.