Walseng, E. *, Wang, B. *, Yang, C., Patel, P., Zhao, C., Wu, H., Dall’Acqua, W., Mazor, Y., Conformation-selective instead of avidity-based binding to tumor associated antigen derived peptide-MHC enables targeting of pMHC low expressing cells by anti-pMHC/anti-CD3 T cell engager DuetMab, Front Immunol, 14, (2023)
Wang, X., Wang, K., Yu, M., Velluto, D., Hong, X., Wang, B., Chiu, A., Melero-Martin, J. M., Tomei, A. A., Ma, M., Engineered immunomodulatory accessory cells improve experimental allogeneic islet transplantation without immunosuppression, Science Advances, 8, eabn0071 (2022)
Wang, B.#, Chen, J., Caserto, J. S., Wang, X., Ma, M.#, An in situ hydrogel-mediated chemo-immunometabolic cancer therapy. Nature Communications, 13, 3821 (2022)
Chen, J.*, Wang, B.*#, Caserto, J. S., Shariati, K., Cao, P., Pan, Y., Xu, Q., Ma, M.#, Sustained Delivery of SARS-CoV-2 RBD Subunit Vaccine Using a High Affinity Injectable Hydrogel Scaffold. Adv Healthc Mater, 11, e2101714 (2022)
Liu, Q., Wang, X., Chiu, A., Liu, W., Fuchs, S., Wang, B., Wang, L. H., Flanders, J., Zhang, Y., Wang, K., Melero-Martin, J. M., Ma, M., A Zwitterionic Polyurethane Nanoporous Device with Low Foreign-Body Response for Islet Encapsulation, Adv Mater, 33, e2102852 (2021)
Wang, X., Maxwell, K. G., Wang, K., Bowers, D. T., Flanders, J. A., Liu, W., Wang, L. H., Liu, Q., Liu, C., Naji, A., Wang, Y., Wang, B., Chen, J., Ernst, A. U., Melero-Martin, J. M., Millman, J. R., Ma, M., A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes, Science Translational Medicine, 13, abb4601 (2021)
Dovedi, S. J., Elder, M. J., Yang, C., Sitnikova, S. I., Irving, L., Hansen, A., Hair, J., Jones, D. C., Hasani, S., Wang, B., Im, S. A., Tran, B., Subramaniam, D. S., Gainer, S. D., Vashisht, K., Lewis, A., Jin, X, Kentner, S., Mulgrew, K., Wang, Y., Overstreet, M. G., Dodgson, J., Wu, Y., Palazon, A., Morrow, M., Rainey, G. J., Browne, G. J., Neal, F., Murray, T. V., Toloczko, A. D., Dall’Acqua, W., Achour, I., Freeman, D. J., Wilkinson, R. W., Mazor, Y., Design and efficacy of a monovalent bispecific PD-1/CTLA-4 antibody that enhances CTLA-4 blockade on PD-1+ activated T cells, Cancer Discovery, 11, 1100-1117 (2021)
Wang, B., Yang C., Jin, X., Du, Q., Wu, H., Dall’Acqua, W., Mazor, Y., Regulation of antibody-mediated complement-dependent cytotoxicity by modulating the intrinsic affinity and binding valency of IgG for target antigen, mAbs, 12, 1690959 (2020)
Wang, B., DeKosky, B. J., Timm, M. R., Lee, J., Normandin, E., Misasi, J., Kong, R., McDaniel, J. R., Delidakis, G., Leigh, K. E., Niezold, T, Choi, C. W., Viox, E. G., Fahad, A., Cagigi, A., Ploquin, A., Leung, K., Yang, E. S., Kong, W. P., Voss, W. N., Schmidt, A. G., Moody, M. A., Ambrozak, D. R., Henry, A. R., Laboune, F., Ledgerwood, J. E., Graham, B. S., Connors, M., Douek, D. C., Sullivan, N. J., Ellington A. D., Mascola, J. R., Georgiou, G., Functional interrogation and mining of natively paired human VH:VL antibody repertoires, Nature Biotechnology, 36, 152-155 (2018)
Tack, D. S., Ellefson, J. W., Thyer, R., Wang, B., Gollihar, J., Forster, M. T., Ellington, A. D., Addicting diverse bacteria to a noncanonical amino acid, Nature Chemical Biolology, 12, 138-140 (2016)
不同生理和病理状态下适应性免疫受体组的解码与挖掘
多组学工具解析与编程细胞信号转导
智能大分子与细胞药物设计
国家高层次青年人才项目
中国药科大学兴药领军学者项目
Walseng, E. *, Wang, B. *, Yang, C., Patel, P., Zhao, C., Wu, H., Dall’Acqua, W., Mazor, Y., Conformation-selective instead of avidity-based binding to tumor associated antigen derived peptide-MHC enables targeting of pMHC low expressing cells by anti-pMHC/anti-CD3 T cell engager DuetMab, Front Immunol, 14, (2023)
Wang, X., Wang, K., Yu, M., Velluto, D., Hong, X., Wang, B., Chiu, A., Melero-Martin, J. M., Tomei, A. A., Ma, M., Engineered immunomodulatory accessory cells improve experimental allogeneic islet transplantation without immunosuppression, Science Advances, 8, eabn0071 (2022)
Wang, B.#, Chen, J., Caserto, J. S., Wang, X., Ma, M.#, An in situ hydrogel-mediated chemo-immunometabolic cancer therapy. Nature Communications, 13, 3821 (2022)
Chen, J.*, Wang, B.*#, Caserto, J. S., Shariati, K., Cao, P., Pan, Y., Xu, Q., Ma, M.#, Sustained Delivery of SARS-CoV-2 RBD Subunit Vaccine Using a High Affinity Injectable Hydrogel Scaffold. Adv Healthc Mater, 11, e2101714 (2022)
Liu, Q., Wang, X., Chiu, A., Liu, W., Fuchs, S., Wang, B., Wang, L. H., Flanders, J., Zhang, Y., Wang, K., Melero-Martin, J. M., Ma, M., A Zwitterionic Polyurethane Nanoporous Device with Low Foreign-Body Response for Islet Encapsulation, Adv Mater, 33, e2102852 (2021)
Wang, X., Maxwell, K. G., Wang, K., Bowers, D. T., Flanders, J. A., Liu, W., Wang, L. H., Liu, Q., Liu, C., Naji, A., Wang, Y., Wang, B., Chen, J., Ernst, A. U., Melero-Martin, J. M., Millman, J. R., Ma, M., A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes, Science Translational Medicine, 13, abb4601 (2021)
Dovedi, S. J., Elder, M. J., Yang, C., Sitnikova, S. I., Irving, L., Hansen, A., Hair, J., Jones, D. C., Hasani, S., Wang, B., Im, S. A., Tran, B., Subramaniam, D. S., Gainer, S. D., Vashisht, K., Lewis, A., Jin, X, Kentner, S., Mulgrew, K., Wang, Y., Overstreet, M. G., Dodgson, J., Wu, Y., Palazon, A., Morrow, M., Rainey, G. J., Browne, G. J., Neal, F., Murray, T. V., Toloczko, A. D., Dall’Acqua, W., Achour, I., Freeman, D. J., Wilkinson, R. W., Mazor, Y., Design and efficacy of a monovalent bispecific PD-1/CTLA-4 antibody that enhances CTLA-4 blockade on PD-1+ activated T cells, Cancer Discovery, 11, 1100-1117 (2021)
Wang, B., Yang C., Jin, X., Du, Q., Wu, H., Dall’Acqua, W., Mazor, Y., Regulation of antibody-mediated complement-dependent cytotoxicity by modulating the intrinsic affinity and binding valency of IgG for target antigen, mAbs, 12, 1690959 (2020)
Wang, B., DeKosky, B. J., Timm, M. R., Lee, J., Normandin, E., Misasi, J., Kong, R., McDaniel, J. R., Delidakis, G., Leigh, K. E., Niezold, T, Choi, C. W., Viox, E. G., Fahad, A., Cagigi, A., Ploquin, A., Leung, K., Yang, E. S., Kong, W. P., Voss, W. N., Schmidt, A. G., Moody, M. A., Ambrozak, D. R., Henry, A. R., Laboune, F., Ledgerwood, J. E., Graham, B. S., Connors, M., Douek, D. C., Sullivan, N. J., Ellington A. D., Mascola, J. R., Georgiou, G., Functional interrogation and mining of natively paired human VH:VL antibody repertoires, Nature Biotechnology, 36, 152-155 (2018)
Tack, D. S., Ellefson, J. W., Thyer, R., Wang, B., Gollihar, J., Forster, M. T., Ellington, A. D., Addicting diverse bacteria to a noncanonical amino acid, Nature Chemical Biolology, 12, 138-140 (2016)
