欧瑜，教授，博导。1995年获南京大学硕士学位，2001年获南京农业大学博士学位，2002.2-2004.3中国药科大学博士后，2015- 2016美国内布拉斯加大学医学中心访问学者。2011年度江苏省 “六大人才高峰”培养对象。长期从事微生物与生化药学教学和科研工作，先后主持国家重大新药创制、江苏省社会发展计划、教育部科学技术研究重点项目等课题，至今以第一和/或通讯作者发表SCI论文20余篇，获专利授权6项，主编专业书3本。主要研究方向为抗代谢性疾病和炎性疾病的生物药物筛选及分子机制研究。
糖脂代谢
重大新药创制专项：抗类风湿一类新药PEG-HM-3临床前研究。
江苏省科技支撑计划-社会发展项目：降糖新药藻蓝蛋白的研究开发。
江苏省“六大人才高峰”人才项目：基于胰岛素信号转导通路探讨藻蓝蛋白抗2型糖尿病机制。
教育部重点项目：重组水蛭素Ⅲ防治糖性白内障的机制研究。
中央高校基本科研业务费专项资金重点基础研究项目：藻蓝蛋白治疗2型糖尿病作用机制的研究。
1. Yunbiao Lu, Rongrong Huang, Zhongkan Sun, Yu Ou*. A bovine milk-derived peptide ameliorates pancreatic β-cell dedifferentiation through PI3K/Akt/FOXO1 signaling in type 2 diabetes. Food & Function, 2023, 14(17):8018-8029.
2. Peng Ma, Yu Ou*. Correlation between the dopaminergic system and inflammation disease: a review. Molecular Biology Reports, 2023, 50(8):7043-7053.
3. Peng Ma, Rongrong Huang, Yu Ou*. A soy glycinin derived octapeptide protects against MCD diet induced non-alcoholic fatty liver disease in mice. Food Science and Human Wellness, 2022, 011(006):1544-1554.
4. Rongrong Huang△, Yunbiao Lu△, Zhifei Xie, Xuegan Yang, Yu Ou*. A bovine milk-derived peptide ameliorates alloxan-injured pancreatic β cells through IRS2/PI3K/Akt signaling. Life Science. 2022, 308:120907.
5. Qihao Li△, Wen Peng△, Zhaoyu Zhang, Xin Pei, Zhongkan Sun, Yu Ou* . A phycocyanin derived eicosapeptide attenuates lung fibrosis development. European Journal Of Pharmacology, 2021, 908:174356.
6. Peng Ma, Rongrong Huang, Jingyao Jiang, Yuan Ding, Tingting Li, Yu Ou*. Potential Use of C-phycocyanin in Non-Alcoholic Fatty Liver Disease. Biochemical and Biophysical Research Communications, 2020, 526(4): 906-912.
7. Zhiheng Ren, Zhifei Xie, Danni Cao, Mufeng Gong, Lei Yang, Zhu Zhou, Yu Ou *. C-Phycocyanin inhibits hepatic gluconeogenesis and increases glycogen synthesis via activating Akt and AMPK in insulin resistance hepatocytes. Food & Function, 2018, 23;9(5):2829-2839.
8. Gaoyong Liao, Bing Gao, Yingnv Gao, Xuegan Yang, Xiaodong Cheng，Yu Ou*. Phycocyanin Inhibits Tumorigenic Potential of Pancreatic Cancer Cells: Role of Apoptosis and Autophagy. Scientific Reports, 2016, 6:34564.
9. Yingnv Gao, Gaoyong Liao, Chenxi Xiang, Xuegan Yang, Xiaodong Cheng*, Yu Ou*. Effects of Phycocyanin on INS-1 Pancreatic β-Cell Mediated by PI3K/Akt/FoxO1 signaling pathway. International Journal of Biological Macromolecules, 2016, 83: 185-194.
10. Yingnv Gao, Chen Liu, Guoqing Wan, Xinshuo Wang, Xiaodong Cheng, Yu Ou*. Phycocyanin prevents methylglyoxal-induced mitochondrial-dependent apoptosis in INS-1 cells by Nrf2. Food & Function, 2016, 7: 1129-1137.
