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李赫羽
职称:教授
邮箱:heyuli@cpu.edu.cn
学院:生命科学与技术学院
实验室:江宁校区学院实验楼二期323室
招生学科:生物学、微生物与生化药学
办公室:江宁校区学院实验楼二期310室
个人简历

代谢与蛋白质动态调控


研究方向

代谢与蛋白质动态调控


主持在研项目情况


近年代表性科研成果

Li H, Liu C, Li R, Zhou L, Ran Y, Yang Q, Huang H, Lu H, Song H, Yang B,  Ru H, Lin S, Zhang L*. AARS1 and AARS2 Sense L-lactate to regulate cGAS as global lysine lactyltransferase. Nature. (IF=50.5) (2024 Oct;634(8036):1229-1237) 

Li H, Zhou F*, Zhang L*. STING, a critical contributor to SARS-CoV-2 immunopathology. Signal Transduct Target Ther. (IF=39.3) (2022 Mar 30;7(1):106)

Li H, Zhou F*, Zhang L*. ADP-riboxanation: a new pyroptosis evasion strategy. J Mol Cell Biol. (IF=8.2) (2022 Mar 21;14(1):mjab077)

Xie F#, Zhou X#, Li H, Su P, Liu S, Li R, Zou J, Wei X, Pan C, Zhang Z, Zheng M, Liu Z, Meng X, Ovaa H, Ten Dijke P*, Zhou F*, Zhang L*. USP8 promotes cancer progression and extracellular vesicle-mediated CD8+ T cell exhaustion by deubiquitinating the TGF-β receptor TβRII. EMBO J. (IF=9.4) (2022 Aug 16;41(16):e108791)

Xie F#, Zhou X#, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L*, Zhou F*. Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling. Nat Commun. (IF=14.7) (2022 Aug 1;13(1):4461)

Xie F#, Su P#, Pan T#, Zhou X, Li H, Huang H, Wang A, Wang F, Huang J, Yan H, Zeng L, Zhang L*, Zhou F*. Engineering Extracellular Vesicles Enriched with Palmitoylated ACE2 as COVID-19 Therapy. Adv Mater. (IF=29.4) (2021 Dec;33(49):e2103471)

Yang Q, Wang B, Zheng Q, Li H, Meng X*, Zhou F*, Zhang L*. A Review of Gut Microbiota-Derived Metabolites in Tumor Progression and Cancer Therapy. Adv Sci (Weinh). (IF=15.1) (2023 May;10(15):e2207366)

 Xie F, Zhou X, Fang M, Li H, Su P, Tu Y, Zhang L, Zhou F*. Extracellular Vesicles in Cancer Immune Microenvironment and Cancer Immunotherapy. Adv Sci (Weinh). (IF=15.1) (2019 Oct 23;6(24):1901779)