唐智超，特聘副研究员，硕士生导师。本科和博士毕业于中国药科大学药物化学专业，毕业后加入南京圣和药业担任研究员和项目经理。2020-2025年先后在堪萨斯大学和芝加哥大学进行博士后研究，2026年加入中国药科大学生命科学与技术学院。
主要研究领域为靶向RNA和RNA结合蛋白的小分子药物发现以及RNA化学生物学。近年来以第一作者在Nature Communications、Nucleic Acids Research等知名期刊发表多篇研究论文。
靶向RNA和RNA结合蛋白的小分子药物发现
与RNA剪接相关的靶点发现和药物开发
中国药科大学高层次人才科研启动经费（主持）
1. Zhichao Tang†, Shalakha Hegde†, Siyuan Hao, Manikandan Selvaraju, Jianming Qiu, Jingxin Wang*. Chemical-guided SHAPE sequencing (cgSHAPE-seq) informs the binding site of RNA-degrading chimeras targeting SARS-CoV-2 5’ untranslated region, Nature Communications, 16, 483 (2025).
2. Zhichao Tang, Sana Akhter, Ankita Ramprasad, Xiao Wang, Mikhail Reibarkh, Jinan Wang, Sadikshya Aryal, Srinivas S Thota, Junxing Zhao, Justin T Douglas, Philip Gao, Erik D Holmstrom, Yinglong Miao, Jingxin Wang*. Recognition of single-stranded nucleic acids by small-molecule splicing modulators, Nucleic Acids Research2021, 49(14), 7870–7883.
3. Shalakha Hegde†, Sana Akhter†, Zhichao Tang†, Chang Qi, Chenguang Yu, Anna Lewicka, Yu Liu, Kushal Koirala, Mikhail Reibarkh, Kevin P. Battaile, Anne Cooper, Scott Lovell, Erik D. Holmstrom, Xiao Wang, Joseph A. Piccirilli, Qi Gao*, Yinglong Miao*, Jingxin Wang*.Mechanistic Studies of Small Molecule Ligands Selective to RNA Single GBulges. Nucleic Acids Research2025, 53(12), gkaf559.
4. Zhichao Tang†, Junxing Zhao†, Ying Li†, Shallu Tomer, Manikandan Selvaraju, Nicholas Tien, Diyun Sun, David K. Johnson, Anjie Zhen, Pingwei Li, Jingxin Wang*. Structural and Biological Evaluations of a Non-Nucleoside STING Agonist Specific for Human STINGA230 Variants. ACS Med. Chem. Lett.2024, 15, 5, 653–658.
5. Zhichao Tang†, Shalakha Hegde†, Junxing Zhao†, Shoutian Zhu, Kristen A. Johnson, Christian L. Lorson, Jingxin Wang*. CRISPR-Mediated Enzyme Fragment Complementation Assay for Quantification of the Stability of Splice Isoforms, ChemBioChem2022, doi: 10.1002/cbic.202200012.
6. Junxing Zhao, Zhichao Tang, Manikandan Selvaraju, Kristen A. Johnson, Justin T. Douglas, Philip F. Gao, H. Michael Petrassi, Michael Zhuo Wang, Jingxin Wang*. Cellular Target Deconvolution of Small Molecules Using a Selection-Based Genetic Screening Platform, ACS Central Science2022, doi.org/10.1021/acscentsci.2c00609.
